Portrait of Isabella I of Castile (1451-1504), 16th century. Anonymous, formerly attributed to Antonio del Rincón (Spanish, 1466-1500). Oil on canvas. Casa de los Tiros.
With her husband Ferdinand, Isabella united the Kingdoms of Spain under a single crown, drove the last of the Moors from the Iberian Peninsula, and supported the voyages of Columbus. Isabella herself played a key role in virtually all of the major developments of Spain during this period and directed most domestic policy.