The “Sweet Child o’ Mine” video depicts the band rehearsing in the Mendiola’s Ballroom at Huntington Park, surrounded by crew members. All of the band members’ girlfriends at the time were shown in the clip: Rose’s girlfriend Erin Everly, whose father was Don Everly of The Everly Brothers; McKagan’s girlfriend Mandy Brix, from the all-female rock band the Lame Flames; Stradlin’s girlfriend Angela Nicoletti; Adler’s girlfriend Cheryl Swiderski; and Slash’s girlfriend Sally McLaughlin. Stradlin’s dog was also featured. The video was successful on MTV, and helped launch the song to success on mainstream radio.
To make “Sweet Child o’ Mine” more marketable to MTV and radio stations, the song was edited down from 5:56 to 4:13, for the radio edit/remix, with much of Slash’s guitar solo removed. This drew the ire of the band, including Rose, who commented on it in a 1989 interview with Rolling Stone: “I hate the edit of ‘Sweet Child O’ Mine.’ Radio stations said, ’Well, your vocals aren’t cut.’My favorite part of the song is Slash’s slow solo; it’s the heaviest part for me. There’s no reason for it to be missing except to create more space for commercials, so the radio-station owners can get more advertising dollars. When you get the chopped version of 'Paradise City’ or half of 'Sweet Child’ and 'Patience’ cut, you’re getting screwed.”