A Scifi and Fantasy Idea

Far in the future, to avoid Entropy and Heat-Death, Humanity has uploaded themselves onto the fabric of space-time itself; “beneath” the quantum field. Effectively gods, so ancient that many of them have lived more in millenia than the universe in modern times have existed in seconds, creating matter and energy through manipulating the quantum layer.

There is only one question left that science has been unable to answer: What will the next universe be like? It has already been confirmed that they will survive a big bang going off, and will survive no matter what alternate physics will be in play, but how it will turn out is completely unable to be predicted.

After aeons of waiting, when the universe has been dead many millions of times longer than it was ever alive in the first place the time finally comes, and a new Big Bang occurs. Humanity collectively watch in anticipation, and then:

They get a front-row seat to an Overgod creating a High-Fantasy D&D-esque cosmology multiverse, complete with Gods, Magic, Elemental, Astral Planes and Far Realms. And they have no idea how any of it works. But Humanity knows one thing. THEY WANT TO KNOW ALL THE THINGS!

How does a ludicrously advanced sci-fi human civilization of might-as-well-be Space!gods and a D&D-like High Fantasy cosmology react to each other?