#haematology
I overheard someone asking a haematology reg why he chose haem and he answered ‘I wanted to be able to sound like a smart-arse’
I respect that
Hi everyone! Long time no see? :D
Today, I’ll be sharing a few facts and mnemonics on hemoglobin and erythropoiesis. Let’s get started!
Do you know the order in which hemoglobin appear from early embryo to infancy?
It’sembryonic hemoglobin first (Gower 1, Gower 2, Portland) then fetal and after that, adult.Mnemonic: Gowergoes,fetalfollows,adultafterwards.
(Also, notice the reverse alphabetical order - G, F, e, d, c, B, A)
The alphabets also pair the chains with their respective hemoglobin!
GF-GammaFetal
BA-BetaAdultGammagoes,becomesbeta, is also a good way to remember the switch from fetal hemoglobin to adult hemoglobin. Alphaalways <3
Why fetal hemoglobin? Because the gamma fraction allows fetal Hb to have higher affinity of it for oxygen which allows it to extract oxygen from maternal blood.
Mnemonic: FetalFetches oxygen Fast.
Did you know the switch from fetal to adult hemoglobin occurs at 38 weeks of gestation in utero? Because I didn’t! I always assumed it was 6 months of life, but that’s when the switch is completed, it is initiated waaay before!
What else? Oh yes, the site of hematopoiesis!
Yolk sac (3-8 weeks)
Liver (6 weeks-birth)
Spleen and lymphatics (10-28 weeks)
Bone marrow (18 weeks to adult)Mnemonic: YoungLifeSynthesizesBlood.
That’s all!
“Noodles, don’t noodles. You’re too concerned with what was and what will be.”
-IkaN
Some causes of haemoptysis. Divided into haematological (red), infectious (green) and malignant (purple) causes.
I’m really proud of the slice of cheese in the TB granuloma. Official way of depicting TB from now on.
Post link
