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Zinc supplementation may exacerbate rheumatoid arthritis (RA), new laboratory data suggest.

In monocytes from rheumatoid arthritis patients, plasma zinc concentrations and Zip8 expression were increased, and Zip8 expression correlated with more severe disease. Thus, inhibiting zinc influx into monocytes and macrophages could prevent excessive inflammatory responses that occur in diseases such as rheumatoid arthritis – the researchers concluded.

Bacteria may Demonstrate any of Five General Mechanisms of Antibiotic Resistance: 
1. Lack of entry; Decreased cell permeability. 
2. Greater exit; Active efflux. 
3. Enzymatic inactivation of the antibiotic. 
4. Altered target; Modification of drug receptor site. 
5. Synthesis of resistant metabolic pathway. 

More than HIV, more than malaria. The death toll worldwide from bacterial antimicrobial resistance (AMR) in 2019 exceeded 1.2 million people, according to a new study. 

In terms of preventable deaths, 1.27 million people could have been saved if drug-resistant infections were replaced with infections susceptible to current antibiotics. Furthermore, 4.95 million fewer people would have died if drug-resistant infections were replaced by no infections, researchers estimated.

A 57-year-old man with life-threatening heart disease has received a heart from a genetically modified pig, a groundbreaking procedure that offers hope to hundreds of thousands of patients with failing organs.

It is the first successful transplant of a pig’s heart into a human being. The eight-hour operation took place in Baltimore, and the patient, David Bennett Sr. of Maryland, was doing well three days later, according to surgeons at the University of Maryland Medical Center.

Researchers say they have found a second patient whose body seemingly had rid itself of the human immunodeficiency virus (HIV) that causes AIDS — supporting hope that it may be possible someday to find a way to cure more people of the virus.

I am a medical student from a developing country in Southeast Europe, the average monthly wages here are around 420 euros. The education system incomparable to the american or  european system, the literature we use is so outdated that our diploma is not recognised outside our county. But we want to be as equally good doctors. Therefore, we try using foreign books and online resources but you know these things usually have a price and my family cannot afford to pay  for my ‘non-university-required’. /optional study materials. I am in my clinical years of med school and I have found the OnlineMedEd videos very useful but I can not afford the OME notes. May ask if anyone could be willing to share the onlinemeded notes pdf with me. I would be really grateful. Sorry for taking your time.  please if you can and want help me. Thank you in advance!

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