#microscopy
Mouse diaphragm consisting of neurons, muscle cells and neuromuscular junctions under the confocal microscope: Green structures show neurons (Alexa 488), red areas are neuromuscular junctions (rhodamin), and blues areas are muscle fiber (myosin, DODT contrast).
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Human epithelial cell in mitosis, fluorescently labeled for alpha tubulin, gamma tubulin and DNA.
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Nearly 2K followers on tumblr! wtf is happening? ;) and now something for this occasion:
Photomicrograph of a midsaggital section showing the different components of the rat cerebellum, including Purkinje neurons in green, glia (non-neuronal cells) in red, and cell nuclei in blue. This image is part of an ongoing effort to develop methods to enable the creation large-scale digital atlases of the brain.
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A human HaCat keratinocyte responds to epidermal growth factor by rapidly forming a lamellipod around most of its perimeter. The cell was fixed and processed within minutes after EGF addition. F-actin is stained with fluorescently labeled phalloidin (light purple), and microtubules are labeled with an antibody (cyan). DNA dye stains the nucleus dark purple.
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Magnesium oxide single crystals growing on Mg. Courtesy of Anasori Babak, Materials Science and Engineering Dpt, Drexel University, Philadel
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Immunostaining of planktonic Cnidaria. Acetylated tubulin (green), myosin (red), nuclei (blue). Image taken with ZEISS Lightsheet Z.1 during the EMBO course on Marine Animal Models in Evolution & Development, Sweden 2013. www.zeiss.com/lightsheet Sample courtesy of Helena Parra, Institut de Biologia Evolutiva (CSIC-Universitat Pompeu Fabra), Barcelona.
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Just 22 hours after fertilization, this zebrafish embryo is already taking shape. By 36 hours, all of the major organs will have started to form. The zebrafish’s rapid growth and see-through embryo make it ideal for scientists studying how organs develop. Image courtesy of Philipp Keller, Bill Lemon, Yinan Wan and Kristin Branson, Janelia Farm Research Campus, Howard Hughes Medical Institute, Ashburn, Va. Part of the exhibit Life:Magnified by ASCB and NIGMS.
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The incredible complexity of a mammalian eye (in this case from a mouse) is captured here. Each color represents a different type of cell. In total, there are nearly 70 different cell types, including the retina’s many rings and the peach-colored muscle cells clustered on the left. Image
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This normal human skin cell was treated with a growth factor that triggered the formation of specialized protein structures that enable the cell to move. We depend on cell movement for such basic functions as wound healing and launching an immune response. Image courtesy of Torsten Wittmann, University of California, San Francisco. Part of the exhibit Life:Magnified by ASCB and NIGMS.
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The parasitic worm that causes schistosomiasis hatches in water and grows up in a freshwater snail, as shown here. Once mature, the worm swims back into the water, where it can infect people through skin contact. Initially, an infected person might have a rash, itchy skin or flu-like symptoms, but the real damage is done over time to internal organs. Image courtesy of o Wang and Phillip A. Newmark, University of Illinois at Urbana-Champaign.
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This pig cell is in the process of dividing. The chromosomes (purple) have already replicated and the duplicates are being pulled apart by fibers of the cell skeleton known as microtubules (green). Studies of cell division yield knowledge that is critical to advancing understanding of many human diseases, including cancer and birth defects. Image courtesy of Nasser Rusan, National Heart, Lung, and Blood Institute, National Institutes of Health.
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The long, spiral-shaped bacterium (gray) in this image causes relapsing fever, a disease characterized by recurring high fevers, muscle aches and nausea. The relapses result from the bacterium’s unusual ability to change the molecules on its outer surface, allowing it to dodge the human immune system. The disease is transmitted through the bite of a tick (not the same species that transmits Lyme disease) and is found in parts of the Americas, the Mediterranean, central Asia and Africa. Image courtesy of Tom Schwan, Robert Fischer and Anita Mora, National Institute of Allergy and Infectious Diseases, National Institutes of Health.
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A mouse’s fat cells (red) are shown surrounded by a network of blood vessels (green). Fat cells store and release energy, protect organs and nerve tissues, insulate us from the cold and help us absorb important vitamins. Image courtesy of Daniela Malide, National Heart, Lung, and Blood Institute, National Institutes of Health.
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