#histotechnology
You can find LOVE in the strangest of places (2022 edition)
By row starting top left:
1. in a skin cylindroma
2. in an hepatic ductule
3. in a pancreas
4. in a warty penile growth
5. in a mucus-y colon
6. in a region of hypodermis
7. in a secondary oocyte
8. in a chondrosarcoma
9. in a small artery
Happy Valentine’s Day
Tag a friend with the histo heart you want to share with them and spread the love!
Images by:
@ihearthisto [1-4, 5-9]
@donna.horncastle [5]
Kitty Liver
Check meowt!
I’m a purrfect hepatic vein surrounded by hepatic lobules!
This is a hematoxylin and eosin stained slice through a liver that was injected with carbon/ink prior to fixation.
The liver is compose of numerous roughly hexagonal shaped lobules. Each lobule has a venule at its center (the central vein; top right) and a series of hepatic triads at its periphery. A triad is a collection of three structures - in this case branches of the hepatic artery, hepatic portal vein and hepatic duct.
Blood in the hepatic artery (oxygenated) and hepatic portal vein (rich in nutrients absorbed from the intestines) travels in sinusoids (the many narrow white spaces in this image) towards the central vein of each lobule. On its way through the sinusoids the blood is processed by the the many hepatocytes that line this region (the pink cells).
Within the sinusoids reside many liver macrophages (Kupffer cells) that phagocytose debris traveling through sinusoids. Normally these cells are invisible in standard H&E preparations but recall that this tissue was injected with ink! The ink was phagocytosed by the macrophages filling their cytoplasm with carbon so that they are now visible as black cells in the sinusoids.
Once the blood enters the central vein of each hepatic lobule they drain into the hepatic veins (kitty!) until the blood reaches the inferior venal cava.
In this way all blood, rich in raw nutrients and toxins absorbed from the GI tract is processed by the liver before it enters the systemic circulation!
Pawsitively unbeliverable!
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Cookie Monster Ovary
Today’s ihearthisto is brought to you by the letter O for Oocyte!
This is image shows a high magnification view of a slice through an ovary.
You are looking at four tiny primordial follicles (the cookies above Cookie Monster’s head) located in the outer cortex of the ovary. Each of these follicles contains a single dormant, immature egg (a primary oocyte) that is halted in the the first phase of meiosis (prophase I). Eventually these follicles will be recruited to enter the maturation cycle that, against all the odds, could see them develop into an embryo.
Cookie monster himself is a larger multilaminar primary follicle (the cookie in his mouth is the nucleus of the oocyte within the follicle). This type of follicle has already been recruited and it’s follicular cells are dividing and differentiating. The oocyte within it though is still halted in prophase I of meiosis.
An oocyte will only complete meiosis if it is ovulated and fertilized by a spermatozoon (a sperm cell).
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Bender-scope
The microscopes of the future are all surly and a little bit hungover.
Current mood: “Bite my shiny metal a$$“
Zomb-hair
A very close-up scene from the hit TV series ‘The Walking Dreads’
This is actually a vibrissae hair follicle from the face of a (a whisker).
Vibrissae are sensory hairs that are different from regular body hairs in the fact that they are surrounded by a blood filled sinus (z’s brain) and are associated with sensory neurons that have a distinct and representative pattern in the somatosensory cortex of the mouse brain. The fact that they are well mapped in the brain illustrates their importance in everyday behavior and survival - they are involved in things like detecting, orienting and sensing length of surfaces/objects and tracking (e.g. finding gaps in a maze and answering the question 'can my head fit through here?’).
Note also the sebaceous glands (z’s eyes) which secrete a lipid rich secretion called sebum for maintaining hair and epidermis keratin (keratin is the wispy stuff lining the skin at the bottom of the image and forming z’s lil arms).
The hair in this follicle is absent as you can see z’s wailing mouth is completely empty (where you might expect to see the shaft of a hair).
The closest things us humans have to vibrissae are the thick long hairs in our nostrils which are fairly sensitive to tickles (and make your eyes water if plucked) but more importantly provide a first line of filtration to prevent big particles from being inhaled into your nasal cavity.
#histology #science #anatomy #pathology #autopsy #pathologists #dermatology #halloween #hair #skin #zombie #dentalstudent #dentalschool #histotech #medlab #premed #meded #nurse #nursing #medschool #medstudent #medicine #vetscience #vetschool #histotechnology #histologia #histo #pathArt #vetstudent #ihearthisto
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