#pathart
☘️Shamrock Gloms ☘️
For each petal on the shamrock,
This brings a wish your way.
Good health. Good luck. Happiness.
For today and every day.
Happy St. Patrick’s Day!
Three renal corpuscles (glomerulus + their surrounding Bowman’s capsules) floating in a sea of distal and proximal convoluted tubules within the cortex of the kidney.
These three small structures are knotted balls of capillaries (glomeruli) surrounded by a specialized epithelium (Bowman’s capsule) that is composed of cells called podocytes. These cells have tiny interlocking legs that form a small slit between them.
This structural organization is responsible for filtering your blood to produce a fluid that then travels within tubes continuous with the Bowman’s capsule called nephrons. In these nephrons the tubular fluid is modified by reabsorbing and secreting ions and conserving water to produce urine for excretion.
Kitty Liver
Check meowt!
I’m a purrfect hepatic vein surrounded by hepatic lobules!
This is a hematoxylin and eosin stained slice through a liver that was injected with carbon/ink prior to fixation.
The liver is compose of numerous roughly hexagonal shaped lobules. Each lobule has a venule at its center (the central vein; top right) and a series of hepatic triads at its periphery. A triad is a collection of three structures - in this case branches of the hepatic artery, hepatic portal vein and hepatic duct.
Blood in the hepatic artery (oxygenated) and hepatic portal vein (rich in nutrients absorbed from the intestines) travels in sinusoids (the many narrow white spaces in this image) towards the central vein of each lobule. On its way through the sinusoids the blood is processed by the the many hepatocytes that line this region (the pink cells).
Within the sinusoids reside many liver macrophages (Kupffer cells) that phagocytose debris traveling through sinusoids. Normally these cells are invisible in standard H&E preparations but recall that this tissue was injected with ink! The ink was phagocytosed by the macrophages filling their cytoplasm with carbon so that they are now visible as black cells in the sinusoids.
Once the blood enters the central vein of each hepatic lobule they drain into the hepatic veins (kitty!) until the blood reaches the inferior venal cava.
In this way all blood, rich in raw nutrients and toxins absorbed from the GI tract is processed by the liver before it enters the systemic circulation!
Pawsitively unbeliverable!
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Prostate Snail
A secretory gastropod with a corpus amylaceum shell!
i❤️histo
This image is a close up view of a slice through the prostate gland!
The glandular portion of the prostate is composed of secretory acini that release prostatic fluid into a duct system within the gland. Prostatic fluid is a major component of semen and is rich in protein and sugar that keeps spermatozoa nourished as they travel through the reproductive tract.
The snail’s head and body are composed of the secretory epithelial cells!
The giant shell of the snail is a structure known as a prostatic concretion (corpus amylaceum or starchy body). This is a substance thought to be composed of thickened prostatic secretions and shed cells that is found in the acini and ducts of the prostate gland - it is of unknown significance.
However, these structures do increase in number with age and are a useful identifying feature of prostate in both non-pathological and pathological prostate specimens.
The space between the secretory acini is filled with a mixture of fibrous connective tissue and smooth muscle.
The smooth muscle is important because it contracts during ejaculation to push the prostatic fluid out of the gland and into the prostatic urethra where it mixes with spermatozoa arriving from the testis.
The connective tissue component is important clinically because as people with prostate glands grow older this fibrous tissue can undergo hyperplasia (excessive growth). This growth can constrict the urethra which passes directly through the prostate gland. The urethra, in addition to conveying semen during ejaculation, also carries urine during micturition/urination. This explains some of the symptoms associated with the common disorder, benign prostatic hyperplasia when urination becomes problematic for the elderly.
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Bender-scope
The microscopes of the future are all surly and a little bit hungover.
Current mood: “Bite my shiny metal a$$“
The Ro-lung Stones
The Stones’ ‘Hot Lips’ logo formed from a blood vessel filled with erythrocytes within a congested zone around a focal pneumonia of the lung.
During the first stages of focal/lobar pneumonia macrophages (the larger cells that are visible in the white alveolar space) respond to phagocytose (eat) any pathogens in the lung.
Additionally, the small blood vessels within the lung tissue begin to engorge (you can see all the erythrocytes in the dilated vessels not only in the large 'hot lips’ vessel but the smaller vessels in the interalveolar septa between adjacent alveoli). This is the congestion phase.
With this dilation of vessels come more white blood cells, you can see numerous neutrophils (they are the small cells that look like they have multiple lobes to their purple nuclei) have migrated out of the vessels (a process called extravasation) into the surround tissue and alveolar spaces. These cells are signs of an additional immune response and they help the macrophages destroy pathogens in the airway.
Image is by @beautiful_pathologist - check out her Instagram for more histology.
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Caaaaarrrggghhh-diovascular Histology
Terrifying a medical student near you this Halloween!
The zombie’s lifeless eyes are arterioles.
His blood-filled mouth is a small vein.
All wrapped up in a connective tissue face.
Happy Halloween Histo fans!
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The Creepiest Fibroblast You Will Ever See
With a nucleus straight from the fiery depths of hell*
*Note: Fibroblasts do not come from hell. They are actually derived from embryonic mesoderm and the creepiest thing they do is secrete the collagen and ground substance of connective tissue. Not very creepy at all really when you think about it.
Histology is from the microscope of the ‘fiancee of ned4spd8834’
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Johnny, don’t leave me
You said you’d love me forever
Honey, believe me
I’ll have your heart on a platter
Ayesha self indulgence
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Chapter 5 spoilers
As soon as I saw that moment, I thought to my self “where have I seen this before- aH YES-”
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Art Summary of 2020
I am very proud of how much I have improved this year compared to last year and I hope I will improve much more the following year!
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strawberry and blue raspberry but make them anime boys
take this as my last drawing for this god forsaken year
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Pomefiore and Scarabia Ayesha
I love the dorm uniforms and I decided to doodle Ayesha in them
Maybe I should do this with the other dorm uniforms..?
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ahaha what if we held hands and…idk…go raid some hilichurl camps and watch the sunset…hahahahah jkjkjkjk….unless..?
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Scarabia
I received a lovely pair of Scarab earrings as a gift from a friend. They were so pretty I couldn’t pass up the opportunity to draw them
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OC Halloween Costume Set
Ayesha - Cute Devil
Angie - Zorro
Carlisle - Undead Frankenstein
Damien - Werewolf
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Happy Birthday Snake Man!!!
(click for better resolution)
I couldn’t celebrate Kalim’s because I just got into the fandom, thank god I noticed Jamil’s so I wanted to make up for it
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